The lyophilizing ability of a series of water-soluble cationic copolymers based on N,N′-diallyl-N,N′-dimethylammonium chloride (DADMAC) was estimated by turbidimetric titration. The copolymer of DADMAC with N-vinylpyrrolidone (DADMAC-VP) that has the best lyophilizing ability was chosen for further modification with betulonic acid (BA) triterpenoid to give ionic complexes with various compositions. The DADMAC-VP/BA complexes were characterized by spectroscopy, thermal analysis, and laser light scattering. The DADMAC-VP/BA complexes self-assemble into nano- and microparticles in aqueous solutions. It has been shown that these particles can solubilize molecules of compounds that are poorly soluble in water.

一系列基于N,N'-二烯丙基-N,N'-二甲基氯化铵 (DADMAC)的水溶性阳离子共聚物的冻干能力通过比浊滴定法进行评估。选择具有最佳冻干能力的 DADMAC 与N-乙烯基吡咯烷酮 (DADMAC-VP)的共聚物，用桦木酸 (BA) 三萜类化合物进一步改性，得到具有各种组成的离子复合物。DADMAC-VP/BA 复合物的特征在于光谱、热分析和激光散射。DADMAC-VP/BA 复合物在水溶液中自组装成纳米和微粒。已经表明，这些颗粒可以溶解难溶于水的化合物分子。