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Towards a better understanding of self-management interventions in type 2 diabetes: A meta-regression analysis
Primary Care Diabetes ( IF 2.9 ) Pub Date : 2021-06-30 , DOI: 10.1016/j.pcd.2021.06.006
Manal M Othman 1 , Hanan Khudadad 2 , Ragae Dughmosh 3 , Asma Syed 4 , Justin Clark 5 , Luis Furuya-Kanamori 6 , Abdul-Badi Abou-Samra 7 , Suhail A R Doi 4
Affiliation  

Aims

Attributes that operationally conceptualize diabetes self-management education (DSME) interventions have never been studied previously to assess their impact on relevant outcomes of interest in people with type 2 diabetes (T2D). The aim of this study was to determine the impact of existing interventions classified by their delivery of skills or information related attributes on immediate (knowledge), intermediate (physical activity), post-intermediate (HbA1c), and long-term (quality of life) outcomes in people with T2D.

Methods

PubMed, Embase, PsycINFO, and Cochrane Library/Cochrane CENTRAL as well as the grey literature were searched to identify interventional studies that examined the impact of DSME interventions on the four different outcomes. Eligible studies were selected and appraised independently by two reviewers. A meta-regression analysis was performed to determine the impact of delivery of the skills- and information-related attributes on the chosen outcomes.

Results

142 studies (n = 25,511 participants) provided data, of which 39 studies (n = 5278) reported on knowledge, 39 studies (n = 8323) on physical activity, 99 studies (n = 17,178) on HbA1c and 24 studies (n = 5147) on quality of life outcomes. Meta-regression analyses demonstrated that skills-related attributes had an estimated effect suggesting improvement in knowledge (SMD [standardized mean difference] increase of 0.80; P = 0.025) and that information-related attributes had an estimated effect suggesting improvement in quality of life (SMD increase of 0.96; P = 0.405). Skill- and information-related attributes did not have an estimated effect suggesting improvement in physical activity or in HbA1c.

Conclusions

The study findings demonstrate that the skills and information related attributes contribute to different outcomes for people with T2D. This study provides, for the first time, preliminary evidence for differential association of the individual DSME attributes with different levels of outcome.



中文翻译:

更好地理解 2 型糖尿病的自我管理干预措施:元回归分析

目标

以前从未研究过在操作上将糖尿病自我管理教育 (DSME) 干预概念化的属性,以评估它们对 2 型糖尿病 (T2D) 患者相关结果的影响。本研究的目的是确定现有干预措施对即时(知识)、中间(身体活动)、后期(HbA1c)和长期(生活质量)的技能或信息相关属性的影响。 ) T2D 患者的结果。

方法

检索了 PubMed、Embase、PsycINFO 和 Cochrane Library/Cochrane CENTRAL 以及灰色文献,以确定检查 DSME 干预对四种不同结果的影响的干预研究。符合条件的研究由两名评审员独立选择和评估。进行元回归分析以确定技能和信息相关属性的交付对所选结果的影响。

结果

142 项研究(n = 25,511 名参与者)提供了数据,其中 39 项研究(n = 5278)报告了知识,39 项研究(n = 8323)关于身体活动,99 项研究(n = 17,178)关于 HbA1c 和 24 项研究(n = 5147)关于生活质量的结果。元回归分析表明,与技能相关的属性具有暗示知识改善的估计效果(SMD [标准化均数差]增加 0.80;P = 0.025),而与信息相关的属性具有暗示生活质量改善的估计效果( SMD 增加 0.96;P = 0.405)。与技能和信息相关的属性没有估计影响身体活动或 HbA1c 的改善。

结论

研究结果表明,与技能和信息相关的属性对 T2D 患者产生不同的结果。本研究首次为个体 DSME 属性与不同结果水平之间的差异关联提供了初步证据。

更新日期:2021-06-30
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