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Complex movement disorders in SARS-CoV-2 infection induced acute disseminated encephalomyelitis
Journal of Neuroimmunology ( IF 3.3 ) Pub Date : 2021-06-30 , DOI: 10.1016/j.jneuroim.2021.577655
Ritwik Ghosh 1 , Souvik Dubey 2 , Arpan Mandal 1 , Biman Kanti Ray 2 , Julián Benito-León 3
Affiliation  

Movement disorders are extremely rare in acute disseminated encephalomyelitis (ADEM) and in the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. We herein report a 34-years-old previously healthy woman who presented with a febrile illness and a constellation of movement disorders (predominantly myoclonus) followed by encephalopathy. After exclusion of common infectious, autoimmune and paraneoplastic etiologies, she was diagnosed to have COVID-19 induced ADEM, which responded to intravenous methylprednisolone and intravenous immunoglobulin. Our case adds to the tally of cases of post-SARS-CoV-2 infection related movement disorders and to the exceedingly rare list of cases in which movement disorders preceded ADEM.



中文翻译:

SARS-CoV-2 感染引起的急性播散性脑脊髓炎的复杂运动障碍

运动障碍在急性播散性脑脊髓炎 (ADEM) 和新型严重急性呼吸系统综合症冠状病毒 (SARS-CoV-2) 感染中极为罕见。我们在此报告了一名 34 岁的既往健康女性,她出现发热性疾病和一系列运动障碍(主要是肌阵挛),随后出现脑病。在排除常见的感染、自身免疫和副肿瘤病因后,她被诊断出患有 COVID-19 诱发的 ADEM,对静脉注射甲泼尼龙和静脉注射免疫球蛋白有反应。我们的病例增加了 SARS-CoV-2 感染后相关运动障碍病例的总数,也增加了运动障碍先于 ADEM 的极为罕见的病例列表。

更新日期:2021-07-12
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