One-step mid- and far-Fourier-transform (FT)-IR spectroscopy is a facile and powerful tool that provides various information regarding chemical and crystal states. However, its potentially high applicability has not been sufficiently demonstrated. In the present study, ibuprofen (IB)-loaded MgO samples are prepared via different methods, and they are evaluated using scanning electron microscopy (SEM), thermogravimetry-differential thermal analysis (TG-DTA), X-ray diffraction analysis (XRD), N₂ adsorption-desorption measurement, CO₂ temperature-programmed desorption technique (CO₂-TPD), and FT-IR spectroscopy. The obtained results indicate that IB becomes ionized, amorphous, and/or dispersed by using MgO. Since the CO₂-TPD result shows that MgO possesses basic surfaces, it is considerable that acid–base interactions cause the above different chemical states. Furthermore, the FT-IR spectra in mid- and far-IR regions also suggest that the above physical and chemical properties of IB-loaded MgO changes through the interactions. Therefore, the characterization results suggest that one-step mid- and far-FT-IR measurements can provide valuable information regarding the chemical and crystal states.

一步式中远傅立叶变换 (FT)-IR 光谱是一种简便而强大的工具，可提供有关化学和晶体状态的各种信息。然而，其潜在的高适用性尚未得到充分证明。在本研究中，通过不同方法制备负载布洛芬 (IB) 的 MgO 样品，并使用扫描电子显微镜 (SEM)、热重-差热分析 (TG-DTA)、X 射线衍射分析 (XRD) 对其进行评估、N ₂吸附-解吸测量、CO _{2 程序}升温解吸技术（CO ₂ -TPD）和FT-IR光谱。获得的结果表明IB通过使用MgO变得电离、无定形和/或分散。由于 CO ₂-TPD结果表明MgO具有碱性表面，酸碱相互作用导致上述不同的化学状态是相当可观的。此外，中红外和远红外区域的 FT-IR 光谱也表明负载 IB 的 MgO 的上述物理和化学性质通过相互作用发生变化。因此，表征结果表明一步中远红外测量可以提供有关化学和晶体状态的有价值的信息。