Heterogeneity has been documented in trajectories of symptom change during antidepressant treatment for major depressive disorder (MDD). It is unclear whether distinct trajectories of change exist for functioning during antidepressant treatment.

中文翻译：

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去甲文拉法辛临床试验中功能和症状变化的轨迹：走向抑郁症的个性化治疗。

在重度抑郁症 (MDD) 的抗抑郁治疗期间，症状变化轨迹中的异质性已被证实。目前尚不清楚在抗抑郁治疗期间是否存在不同的功能变化轨迹。