Background. Peptic ulcer disease (PUD) remains one of the most prevalent gastrointestinal diseases and has been linked to Helicobacter pylori (H. pylori) infection. This condition may be suspected on clinical grounds, but diagnosis is established using upper gastrointestinal endoscopy. Aims. To determine the correlation between the endoscopic and pathological findings among suspected PUD patients who have been referred for diagnostic upper gastrointestinal endoscopy in National Hospital Abuja. Methods. This is a hospital-based prospective study conducted among suspected PUD patients at National Hospital Abuja over a one-year period. Clinical, endoscopic, and histological findings were ascertained and documented. Data obtained were analyzed using SPSS version 21.0. Tests of significance were done using the chi-square test and Student -test at 95% confidence intervals. Results. One hundred and thirty-two patients were included in the study. The ages ranged from 15 to 87 years, mean age years. Seventy-seven (58.3%) patients had abnormal endoscopic findings, of whom 37 (28.0%) had PUD. Prevalence of H. pylori infection was 42.2% and was found in 81.1% of PUD patients. H. pylori was significantly associated with confirmed PUD () and abnormal endoscopic findings (). No association was found between normal endoscopic findings and histological findings (). Conclusion. There is a poor correlation between clinical and endoscopic diagnoses of PUD. H. pylori was found to be significantly associated with PUD and abnormal endoscopic findings. Endoscopic facilities should therefore be made available and accessible for proper PUD diagnosis. Empirical treatment of H. pylori in patients with diagnosed PUD is strongly recommended.

中文翻译：

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尼日利亚阿布贾疑似消化性溃疡病患者的临床、内镜和病理结果的相关性

背景。消化性溃疡病 (PUD) 仍然是最普遍的胃肠道疾病之一，并且与幽门螺杆菌( H. pylori ) 感染有关。临床上可能怀疑这种情况，但通过上消化道内窥镜检查可以确定诊断。目标。确定在阿布贾国立医院接受诊断性上消化道内镜检查的疑似 PUD 患者的内镜检查和病理结果之间的相关性。方法. 这是一项以医院为基础的前瞻性研究，在阿布贾国家医院的疑似 PUD 患者中进行，为期一年。确定并记录临床、内窥镜和组织学发现。使用 SPSS 21.0 版分析获得的数据。使用卡方检验和学生检验进行显着性检验，置信区间为 95%。结果。该研究包括 132 名患者。年龄从 15 岁到 87 岁不等，平均年龄年。77 名 (58.3%) 患者内镜检查结果异常，其中 37 名 (28.0%) 患有 PUD。幽门螺杆菌感染率为 42.2%，在 81.1% 的 PUD 患者中发现。H. pylori与确诊的 PUD 显着相关（)和异常的内镜检查结果 (）。未发现正常内镜检查结果与组织学检查结果之间存在关联（）。 结论。PUD的临床和内镜诊断之间的相关性较差。H. pylori被发现与 PUD 和异常内镜检查结果显着相关。因此，应提供内窥镜设施，以便进行正确的 PUD 诊断。强烈建议对确诊为 PUD 的患者进行H. pylori的经验性治疗