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Effects of blood flow characteristics on rupture of cerebral aneurysm: Computational study
International Journal of Modern Physics C ( IF 1.9 ) Pub Date : 2021-06-28 , DOI: 10.1142/s0129183121501436
Xiao-Yong Shen 1 , M. Barzegar Gerdroodbary 2 , Amin Poozesh 3 , Amir Musa Abazari 4 , S. Misagh Imani 2
Affiliation  

In recent decades, cardiovascular disease and stroke are recognized as the most important reason for the high death rate. Irregular bloodstream and the circulatory system are the main reason for this issue. In this paper, Computational Fluid dynamic method is employed to study the impacts of the flow pattern inside the cerebral aneurysm for detection of the hemorrhage of the aneurysm. To achieve a reliable outcome, blood flow is considered as a non-Newtonian fluid with a power-law model. In this study, the influence of the blood viscosity and velocity on the pressure distribution and average wall shear stress (AWSS) are comprehensively studied. Moreover, the flow pattern inside the aneurysm is investigated to obtain the high-risk regions for the rupture of the aneurysm. Our results indicate that the wall shear stress (WSS) increases with increasing blood flow velocity. Furthermore, the risk of aneurysm rupture is considerably increased when the AWSS increases more than 0.6. Indeed, the blood flow with high viscosity expands the high-risk region on the wall of the aneurysm. Blood flow indicates that the angle of the incoming bloodstream is substantially effective in the high-risk region on the aneurysm wall. The augmentation of the blood velocity and vortices considerably increases the risk of hemorrhage of the aneurysm.

中文翻译:

血流特征对脑动脉瘤破裂的影响:计算研究

近几十年来,心血管疾病和中风被认为是导致高死亡率的最重要原因。不规则的血流和循环系统是这个问题的主要原因。本文采用计算流体动力学方法研究脑动脉瘤内流动模式对动脉瘤出血检测的影响。为了获得可靠的结果,血流被视为具有幂律模型的非牛顿流体。本研究全面研究了血液粘度和流速对压力分布和平均壁面剪切应力(AWSS)的影响。此外,研究动脉瘤内部的流动模式,以获得动脉瘤破裂的高风险区域。我们的结果表明,壁剪切应力(WSS)随着血流速度的增加而增加。此外,当 AWSS 增加超过 0.6 时,动脉瘤破裂的风险显着增加。事实上,高粘度的血流扩大了动脉瘤壁上的高风险区域。血流表明流入血流的角度在动脉瘤壁上的高风险区域基本有效。血流速度和涡流的增加显着增加了动脉瘤出血的风险。血流表明流入血流的角度在动脉瘤壁上的高风险区域基本有效。血流速度和涡流的增加显着增加了动脉瘤出血的风险。血流表明流入血流的角度在动脉瘤壁上的高风险区域基本有效。血流速度和涡流的增加显着增加了动脉瘤出血的风险。
更新日期:2021-06-28
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