In the mid 1990s, Lu and co-workers reported the nucleophilic phosphine-triggered annulation reactions of allen- oates with electron-deficient olefins or imines. As one of the most efficient and straightforward synthetic strategies for the construction of highly functionalized carbocycle or heterocycle structural motifs, the development and application of nucleo- philic phosphine-triggered annulation of allenoates by using various nucleophilic phosphines and electron-deficient partners have attracted more and more interests of chemists over the past decades. Furthermore, the development of asymmetric phosphine-triggered annulation of allenoates cleaved a new way to the total synthesis of bioactive natural products and me- dicinally important substances. In addition, aldehydes and ketones were also employed into this reaction, leading to a wide range of O-fused heterocycles. This review focuses on the important developments concerning racemic and asymmetric an- nulation reactions of allenoates in the past two decades.

中文翻译：

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亲核膦引发的烯丙酸酯环化反应的新进展

在 1990 年代中期，Lu 及其同事报道了烯酸与缺电子烯烃或亚胺的亲核膦引发的环化反应。作为构建高度功能化的碳环或杂环结构基序的最有效和最直接的合成策略之一，通过使用各种亲核膦和缺电子伙伴来开发和应用亲核膦触发的烯丙酸酯环化已经吸引了越来越多的关注。过去几十年化学家的更多兴趣。此外，不对称膦引发的烯丙酸环化的发展为生物活性天然产物和重要药用物质的全合成开辟了一条新途径。此外，醛和酮也用于该反应，导致广泛的O-稠合杂环。本综述重点关注过去二十年中烯丙酸酯的外消旋和不对称环化反应的重要进展。