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Thymopentin alleviates premature ovarian failure in mice by activating YY2/Lin28A and inhibiting the expression of let-7 family microRNAs
Cell Proliferation ( IF 8.5 ) Pub Date : 2021-06-28 , DOI: 10.1111/cpr.13089
Te Liu 1 , Fangyuan Jing 1 , Peirong Huang 2, 3 , Zixiang Geng 4 , Jianghong Xu 5 , Jiahui Li 5 , Danping Chen 5 , Ying Zhu 5 , Zhenxin Wang 6 , Willian Huang 7 , Chuan Chen 1
Affiliation  

Thymopentin (5TP) significantly improved typical murine premature ovarian failure (POF) symptoms induced by a high-fat and high-sugar (HFHS) diet. However, its effect and mechanism remain unclear.

中文翻译:

胸腺五肽通过激活 YY2/Lin28A 和抑制 let-7 家族 microRNA 的表达减轻小鼠卵巢早衰

胸腺五肽 (5TP) 显着改善了由高脂肪和高糖 (HFHS) 饮食引起的典型小鼠卵巢早衰 (POF) 症状。然而,其作用和机制尚不清楚。
更新日期:2021-08-09
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