Objectives

The EDTMP (ethylenediamine-tetra-methylene phosphonate) is a molecule similar to EDTA (ethylenediamine-tetra-acetic acid), but with phosphonates, thereby presenting efficient chelating action and binding adequately to proteins, such as collagen. The objective of this study was to evaluate EDTMP as new etching solution to aid ion-releasing adhesive containing beta-tri-calcium phosphate (β-TCP) fillers used for intrarradicular dentin bonding.

Materials and methods

Thirty extracted single-rooted human teeth were prepared, and glass-fiber posts were adhesively luted with Scotchbond Multipurpose (SBMP, 3 M) adhesive after etching with 37% phosphoric acid for 15s, 15% EDTA or 15% EDTMP for 120s, and SBMP adhesive incorporated or not with β-TCP. RelyX ARC (3 M) was used as resin cement. The restored roots were cut horizontally in 1 mm-thick slabs and submitted to push-out bond strength test after 24h and 6 months of water storage. Interfacial silver nanoleakage was investigated in scanning electron microscopy. Micro-Raman spectroscopy was employed to track mineralization at the hybrid layer. Data were submitted to two-way ANOVA and Tukey’s test (p<0.05).

Results

EDTMP without β-TCP achieved the overall highest bond strength in both storage times. The addition of β-TCP impaired the improvements of EDTMP. The presence of carbonated apatite (peak at 1090 cm^-1) was found in EDTMP without β-TCP, thereby suggesting remineralization. Little silver impregnation was observed in general across groups. Conclusion: EDTMP could be an optimal alternative as root dentin etchant for luting glass-fiber posts with improvements in dentin bond stability.

中文翻译：

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使用治疗性粘合剂和新型牙本质调理剂进行根管内粘合

目标

的EDTMP（乙二胺四亚甲基膦酸盐）类似于EDTA（乙二胺四乙酸）的分子，但膦酸盐，从而呈现有效螯合作用和充分地结合于蛋白质，如胶原。本研究的目的是评估 EDTMP 作为新的蚀刻溶液，以辅助离子释放粘合剂，其中包含用于根内牙本质粘接的β-磷酸三钙 (β-TCP) 填料。

材料和方法

制备三十提取单根人类牙齿，和玻璃纤维桩进行粘合剂与SCOTCHBOND多用途（SBMP，3 M）用37％磷酸15秒，15％EDTA或15％EDTMP 120秒蚀刻后的粘合剂，和SBMP luted粘合剂结合或不与β-TCP。RelyX ARC（3 M）作为树脂粘固剂。恢复的根在1mm厚的板坯水平地切割和水存储的24h和6个月后提交给顶出粘合强度试验。界面银纳米渗漏在扫描电子显微镜进行了研究。显微喇曼光谱采用在该混合层来跟踪矿化。数据被提交给双向ANOVA和Tukey检验（P <0.05）。

结果

EDTMP没有β-TCP在两个存储时间实现总体最高粘结强度。添加β-TCP受损EDTMP的改进。碳酸磷灰石（峰在1090厘米存在^-1）在EDTMP发现没有β-TCP，从而表明再矿化。一般来说，观察各组小银浸渍。结论：EDTMP可能是一个最佳的选择，因为根牙质蚀刻剂LUTING玻璃纤维根柱与牙本质粘合稳定性的改进。