Bulletin of Experimental Biology and Medicine ( IF 0.7 ) Pub Date : 2021-06-26 , DOI: 10.1007/s10517-021-05212-5 S N Abdreshov 1 , G A Demchenko 1 , A T Mamataeva 1 , G K Atanbaeva 2 , S A Mankibaeva 2 , N A Akhmetbaeva 1 , U N Kozhaniyazova 1 , U B Nauryzbai 1
We used specific histochemical fluorescence-microscopic method of visualization of catecholamines to study adrenergic innervation of the thyroid gland tissue, blood vessels of the thyroid gland, cervical lymphatic vessel and lymph nodes in rats during correction of hypothyroidism with a bioactive formulation (Vozrozhdenie Plus balm with Potentilla alba L.). In experimental hypothyroidism, adrenergic innervation of the thyroid gland and the wall of the cervical lymph node, concentrated mainly along the arterial vessels and the cervical lymphatic vessel, retained its structural formations (plexuses and varicosities), but diffusion of catecholamines outside these formations was observed. Correction with the bioactive formulation restored of the contours of the nerve plexuses and varicosities and their brighter fluorescence in the thyroid gland and cervical lymphatic vessel and node. During correction of hypothyroidism with the bioactive formulation, reorganization of regional lymphatic vessels and nodes was more pronounced than reorganization of the thyroid gland.
中文翻译:
甲状腺功能减退症矫正过程中甲状腺、血液和淋巴管及淋巴结的肾上腺素能神经支配状况
我们使用特定的组织化学荧光显微镜观察儿茶酚胺的方法来研究大鼠甲状腺组织、甲状腺血管、颈部淋巴管和淋巴结在使用生物活性制剂(Vozrozhdenie Plus balm with白委陵菜L.)。在实验性甲状腺功能减退症中,甲状腺和颈部淋巴结壁的肾上腺素能神经支配,主要集中在动脉血管和颈部淋巴管,保留其结构结构(丛和静脉曲张),但观察到儿茶酚胺扩散到这些结构之外. 用生物活性制剂进行矫正,恢复了神经丛和静脉曲张的轮廓,并在甲状腺和颈部淋巴管和淋巴结中发出更亮的荧光。在用生物活性制剂纠正甲状腺功能减退期间,局部淋巴管和淋巴结的重组比甲状腺的重组更明显。