We developed a model of retinal degeneration in rabbits based on exposure to light with a wavelength of 405 nm. This model allows reproducing structural and functional disorders in the central parts of the retina, including primarily degeneration of the outer layers of the retina (retinal pigment epithelium and layer of photoreceptor cells), and is designed to study the mechanisms of formation, progression and effectiveness of new drugs and methods of treatment of degenerative diseases of the retina.

中文翻译：

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视网膜变性的建模

我们基于暴露于波长为 405 nm 的光开发了兔视网膜变性模型。该模型允许再现视网膜中央部分的结构和功能障碍，主要包括视网膜外层（视网膜色素上皮和感光细胞层）的退化，旨在研究形成、进展和有效性的机制治疗视网膜退行性疾病的新药物和方法。