In total hip arthroplasty, the hip joint is replaced by artificial materials. The fibrous tissue that re-forms around the hip joint after surgery plays an important role in joint stability. Here, the morphological and mechanical properties of the scar tissue that forms around implants composed of either polymer and metal or ceramic are compared with native tissue removed during an initial total hip arthroplasty. Immunohistological analyses of the samples revealed different hierarchical structures of the tissues over three scales: the fiber, the fascicle, and tissue scales. At the tissue scale, microtensile tests were performed on millimetric samples and their nonlinear elastic responses identified by either an exponential law or Ogden third-order constitutive model. At the fiber scale, a patient-specific microscale finite element model was used ,including the measured morphological parameters and distinct Ogden constitutive models for the fiber and matrix composed of a mixture of fibers in ground substance.

在全髋关节置换术中，髋关节被人造材料取代。手术后在髋关节周围重新形成的纤维组织在关节稳定性方面起着重要作用。在这里，由聚合物和金属或陶瓷组成的植入物周围形成的疤痕组织的形态和机械特性与初始全髋关节置换术中去除的天然组织进行了比较。样本的免疫组织学分析揭示了组织在三个尺度上的不同层次结构：纤维、束状结构和组织尺度。在组织尺度上，对毫米样品及其非线性弹性响应进行了微拉伸测试，这些响应由指数定律或奥格登三阶本构模型确定。在纤维尺度上，使用了患者特定的微尺度有限元模型，