Abstract A series of novel imidazo[4,5-b]pyridine derivatives were synthesized and their structures were characterized by NMR spectroscopy, mass spectrometry and elemental analysis. The results of bioassays showed that some compounds exhibit good fungicidal activity against Puccinia polysora In particular, compound 7b showed an EC50 value of 4.00 mg/L, which was comparable with that of tebuconazole. Besides, preliminary structure-activity relationship was discussed.

中文翻译：

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新型咪唑并[4, 5-b]吡啶衍生物的合成及杀菌活性

摘要 合成了一系列新型咪唑并[4,5-b]吡啶衍生物，并通过核磁共振谱、质谱和元素分析对其结构进行了表征。生物测定结果表明，部分化合物对多肉锈菌表现出良好的杀菌活性，特别是化合物7b的EC50值为4.00mg/L，与戊唑醇相当。此外，初步讨论了构效关系。