当前位置: X-MOL 学术Heterocycl. Commun. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A Green Synthesis and Antibacterial Activity of N-Arylsulfonylhydrazone Compounds
Heterocyclic Communications ( IF 2.3 ) Pub Date : 2019-12-31 , DOI: 10.1515/hc-2019-0023
Qian Yang 1 , Wangwang Hao 1 , Yangqing He 1 , Qian Zhang 1 , Xiaojiao Yu 1 , Yaobing Hua 1
Affiliation  

Abstract A green method has been developed for the synthesis of N-arylsulfonylhydrazones via a simple grindstone procedure. By grinding mixtures of benzensulfonyl hydrazides and a series of aryl aldehydes or ketones in the mortar using L-tyrosine as catalyst, 24 N-arylsulfonylhydrazones were synthesized in a few minutes with high yield. All compounds were screened for their antibacterial activities. Most of them exhibit some antibacterial activities especially for 3d, 3l and 3v showing high activity against Staphylococcus aureus and Escherichia coli.

中文翻译:

N-芳基磺酰腙类化合物的绿色合成及抗菌活性

摘要 开发了一种通过简单的磨石程序合成 N-芳基磺酰腙的绿色方法。通过使用L-酪氨酸作为催化剂在研钵中研磨苯磺酰肼和一系列芳基醛或酮的混合物,在几分钟内以高产率合成了24个N-芳基磺酰腙。筛选所有化合物的抗菌活性。它们中的大多数表现出一定的抗菌活性,特别是对 3d、3l 和 3v 显示出对金黄色葡萄球菌和大肠杆菌的高活性。
更新日期:2019-12-31
down
wechat
bug