Outpatient neurosurgery is rising popularity leading to patients’ satisfaction and cost-savings. Although several North-American teams have shown the safety of outpatient stereotactic brain biopsies, few data from other countries with different health care systems are available. We therefore conducted a feasibility and safety study on the outpatient stereotactic brain biopsies. We prospectively examined all the consecutive stereotactic brain biopsies performed in an outpatient setting at our tertiary medical center, between June 2018 and September 2020. Among the 437 patients who underwent stereotactic brain biopsy during the study period, 40 (9.2%) patients were enrolled for an outpatient management. The sex ratio was 1 and the median age on biopsy day was 55 [41–66] years. The median distance from patients’ home to hospital was 17 km [3–47]. 95% of patients had pre-biopsy ASA score of 1 or 2 and mRs equal to 2 or less. The rate of same-day discharge was 100%. No patient experienced post-biopsy symptomatic complication necessitating readmission within the month following the biopsy. One patient (2.5%) resorted to an unplanned consultation. Histological findings obtained from brain biopsy led to a diagnosis in all patients; the most frequently found were neoplastic lesions (77.5%). Stereotactic brain biopsies can therefore be safely achieved on an outpatient setting in carefully selected patients. This process could be more widely adopted in other neurosurgical centers, without affecting the quality of patient’s health care and safety. In this article, we propose management guidelines and pre-biopsy checklist for performing ambulatory stereotactic brain biopsies.

门诊神经外科越来越受欢迎，从而提高了患者的满意度并节省了成本。尽管几个北美团队已经证明了门诊立体定向脑活检的安全性，但很少有来自其他具有不同医疗保健系统的国家的数据可用。因此，我们对门诊立体定向脑活检进行了可行性和安全性研究。我们前瞻性地检查了 2018 年 6 月至 2020 年 9 月在我们的三级医疗中心门诊进行的所有连续立体定向脑活检。在研究期间接受立体定向脑活检的 437 名患者中，40 名 (9.2%) 患者入组门诊管理。性别比为 1，活检日的中位年龄为 55 [41-66] 岁。从患者家到医院的中位距离为 17 公里 [3-47]。95% 的患者活检前 ASA 评分为 1 或 2，mR 等于或小于 2。当天出院率为100%。没有患者在活检后一个月内出现需要重新入院的活检后症状性并发症。一名患者 (2.5%) 求助于计划外的会诊。从脑活检中获得的组织学结果对所有患者进行了诊断；最常见的是肿瘤性病变（77.5%）。因此，可以在精心挑选的患者的门诊环境中安全地进行立体定向脑活检。这一过程可以在其他神经外科中心更广泛地采用，而不会影响患者的医疗保健质量和安全。在本文中，我们提出了用于进行动态立体定向脑活检的管理指南和活检前检查表。