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Binge eating behavior and incentive motivation with a cafeteria diet
Behavioural Processes ( IF 1.3 ) Pub Date : 2021-06-24 , DOI: 10.1016/j.beproc.2021.104447
Nayeli Valeria Vazquez-Herrera 1 , Wendy Andrea Zepeda-Ruiz 1 , David N Velazquez-Martinez 1
Affiliation  

Binge-like eating behavior (BLE) has been characterized as an eating disorder in which subjects have an enhanced intake of food, mainly fats. However, intake of fats and carbohydrates may have differential effects on motivation. Previously it was shown that BLE produces an increase in operant responding for vegetable shortening, but others were unable to replicate the finding using sucrose as the reinforcer. Our aim was to determine if BLE behavior induced with a cafeteria-like diet (CaLD) with several options with fat content would produce an increment in performance. Male Wistar rats were trained under an exponential progressive ratio schedule of sucrose reinforcement; thereafter, the limited access model was used to induce BLE using CaLD options. Finally, subjects were tested for increments in break points (BPs) in the progressive ratio schedule. Rats with intermittent access to CaLD options showed a clear BLE with an escalation in their intake; however they showed compensatory decrements of chow intake that rendered a similar body weight gain to a continuous access group. Although we were unable to observe an increase in BPs after BLE we were able to observe a protection against the decrements of BP previously observed with sugar. Different mechanisms for processing high fat and high carbohydrate reinforcers are variables worth exploring to gain a better understanding of BLE behavior in rodent models.



中文翻译:

自助餐厅饮食的暴饮暴食行为和激励动机

暴饮暴食行为 (BLE) 已被描述为一种饮食失调,其中受试者摄入的食物(主要是脂肪)增加。然而,脂肪和碳水化合物的摄入可能对动机有不同的影响。以前的研究表明,BLE 会增加对植物起酥油的操作性反应,但其他人无法使用蔗糖作为强化剂来复制这一发现。我们的目标是确定通过类似自助餐厅的饮食 (CaLD) 和多种脂肪含量选项诱导的 BLE 行为是否会提高性能。雄性 Wistar 大鼠在蔗糖强化的指数渐进比率计划下接受训练;此后,限制访问模型用于使用 CaLD 选项诱导 BLE。最后,在渐进式比率计划中测试受试者的断点 (BP) 增量。间歇性使用 CaLD 选项的大鼠表现出明显的 BLE,其摄入量增加;然而,他们表现出食物摄入量的补偿性减少,使体重增加与连续摄入组相似。虽然我们无法观察到 BLE 后 BP 的增加,但我们能够观察到对先前用糖观察到的 BP 下降的保护作用。处理高脂肪和高碳水化合物强化剂的不同机制是值得探索的变量,以更好地了解啮齿动物模型中的 BLE 行为。然而,他们表现出食物摄入量的补偿性减少,使体重增加与连续摄入组相似。虽然我们无法观察到 BLE 后 BP 的增加,但我们能够观察到对先前用糖观察到的 BP 下降的保护作用。处理高脂肪和高碳水化合物强化剂的不同机制是值得探索的变量,以更好地了解啮齿动物模型中的 BLE 行为。然而,他们表现出食物摄入量的补偿性减少,使体重增加与连续摄入组相似。虽然我们无法观察到 BLE 后 BP 的增加,但我们能够观察到对先前用糖观察到的 BP 下降的保护作用。处理高脂肪和高碳水化合物强化剂的不同机制是值得探索的变量,以更好地了解啮齿动物模型中的 BLE 行为。

更新日期:2021-06-28
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