当前位置: X-MOL 学术Nat. Cancer › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A Wnt twist in FTO’s role in cancer progression
Nature Cancer ( IF 22.7 ) Pub Date : 2021-06-23 , DOI: 10.1038/s43018-021-00224-6
Albertas Navickas 1, 2, 3, 4 , Hani Goodarzi 1, 2, 3, 4
Affiliation  

FTO, an m6A RNA demethylase, is known mainly as an oncoprotein in various cancer types. FTO is now shown to act as a cancer suppressor in a subset of epithelial tumors through an interplay between epithelial-to-mesenchymal transition and Wnt signaling.

中文翻译:

FTO 在癌症进展中的作用的 Wnt 扭曲

FTO 是一种 m6A RNA 去甲基化酶,主要被认为是各种癌症类型中的一种癌蛋白。现在显示 FTO 通过上皮间质转化和 Wnt 信号传导之间的相互作用在上皮肿瘤的一个子集中充当癌症抑制因子。
更新日期:2021-06-24
down
wechat
bug