This prospective study evaluated the 3-year change in menstrual function and bone mass among 40 female adolescent endurance runners (age 15.9 ± 1.0 years) according to baseline disordered eating status. Three years after initial data collection, runners underwent follow-up measures including the Eating Disorder Examination Questionnaire and a survey evaluating menstrual function, running training, injury history, and prior sports participation. Dual-energy X-ray absorptiometry was used to measure bone mineral density and body composition. Runners with a weight concern, shape concern, or global score ≥4.0 or reporting >1 pathologic behavior in the past 28 days were classified with disordered eating. Compared with runners with normal Eating Disorder Examination Questionnaire scores at baseline, runners with disordered eating at baseline reported fewer menstrual cycles/year (6.4 ± 4.5 vs. 10.5 ± 2.8, p = .005), more years of amenorrhea (1.6 ± 1.4 vs. 0.3 ± 0.5, p = .03), and a higher proportion of menstrual irregularity (75.0% vs. 31.3%, p = .02) and failed to increase lumbar spine or total hip bone mineral density at the 3-year follow-up. In a multivariate model including body mass index and menstrual cycles in the past year at baseline, baseline shape concern score (B = −0.57, p value = .001) was inversely related to the annual number of menstrual cycles between assessments. Weight concern score (B = −0.40, p value = .005) was inversely associated with lumbar spine bone mineral density Z-score change between assessments according to a multivariate model adjusting for age and body mass index. These finding support associations between disordered eating at baseline and future menstrual irregularities or reduced accrual of lumbar spine bone mass in female adolescent endurance runners.

这项前瞻性研究根据基线饮食失调状态评估了 40 名女性青少年耐力跑者（年龄 15.9 ± 1.0 岁）的 3 年月经功能和骨量变化。在初始数据收集三年后，跑步者接受了后续措施，包括饮食失调检查问卷和评估月经功能、跑步训练、受伤史和先前运动参与情况的调查。双能 X 线骨密度仪用于测量骨矿物质密度和身体成分。在过去 28 天内存在体重问题、体型问题或总体评分≥4.0 或报告 >1 病理行为的跑步者被归类为饮食失调。与基线时饮食失调检查问卷分数正常的跑步者相比，p  = .005），闭经年限更长（1.6 ± 1.4 vs. 0.3 ± 0.5，p  = .03），月经不规律比例更高（75.0% vs. 31.3%，p  = .02）并且没有增加3 年随访时的腰椎或总髋骨密度。在包括过去一年基线体重指数和月经周期的多变量模型中，基线形状关注评分（B  = -0.57，p值 = .001）与评估之间的年度月经周期数成反比。体重关注评分（B  = -0.40，p值 = .005）与腰椎骨矿物质密度Z呈负相关-根据针对年龄和体重指数进行调整的多变量模型，评估之间的分数变化。这些发现支持基线饮食失调与未来月经不规律或女性青少年耐力跑者腰椎骨量减少之间的关联。