This paper will cover challenges and learnings from implementing layer of protection analysis (LOPA) in a Global organization. The challenges include a wide range of different processes, multiple functional organizations and different country guidance and regulations. The learning will include methods used for streamlining LOPA and communicating consistent LOPA guidance. LOPA is better used as a comparison tool than as an absolute measure of risk. For LOPA results to be comparable, common standards need to be used within the LOPA technique. The paper will cover some of the methods used to embed LOPA practices including: (1) Guidance using worked examples. (2) Templates for similar equipment. (3) Using an internal LOPA governance board to review complicated LOPAs. (4) Use of common software.(5) Strong interfaces between LOPA and safety instrumented function development.

中文翻译：

---

在全球组织中实施保护层分析

本文将介绍在全球组织中实施保护层分析 (LOPA) 的挑战和经验教训。挑战包括范围广泛的不同流程、多个职能组织以及不同国家的指导和法规。学习将包括用于简化 LOPA 和传达一致的 LOPA 指导的方法。LOPA 更适合用作比较工具，而不是绝对风险度量。为了使 LOPA 结果具有可比性，需要在 LOPA 技术中使用通用标准。本文将介绍一些用于嵌入 LOPA 实践的方法，包括： (1) 使用工作示例的指导。(2) 类似设备的模板。(3) 使用内部 LOPA 治理委员会来审查复杂的 LOPA。(4) 使用常用软件。