SummaryIn this study, differential mRNA expression patterns of prolactin receptor (PRLR) in the hypothalamus and gonads, and the correlation with follicle stimulating hormone (FSH) and luteinizing hormone (LH) in striped hamster serum from spring, summer, autumn and winter were analyzed. Mature female and male striped hamsters in oestrus were used. Expression levels of PRLR in the hypothalamus, ovaries and testis from the summer and winter individuals were significantly higher compared with levels from the spring and autumn, whereas FSH and LH serum concentrations from summer and winter individuals were significantly lower compared with that from the spring and autumn. PRLR expression levels in hypothalamus, ovaries and testis were negatively correlated with FSH and LH serum concentrations, illustrating that PRLR might negatively regulate seasonal reproductive activity. PRLR expression levels in ovaries and testes were significantly higher compared with levels in the hypothalamus, suggesting that the regulative effects of PRLR in gonads might be significantly higher compared with that in the hypothalamus. Furthermore, PRLR expression levels from the spring, summer, autumn and winter seasons in the hypothalamus and gonads were significantly higher in females compared with levels in males, indicating that the regulative effect of PRLR might be sex dependent. Taken together, this study helps to understand in depth the seasonal regulative reproduction mechanism of striped hamsters to reasonably control population abundance.

中文翻译：

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催乳素受体调节条纹仓鼠的季节性繁殖

摘要本研究分析了春夏秋冬季条纹仓鼠血清下丘脑和性腺催乳素受体（PRLR）的差异mRNA表达模式，以及与促卵泡激素（FSH）和黄体生成素（LH）的相关性。 . 使用发情期的成熟雌性和雄性条纹仓鼠。夏季和冬季个体下丘脑、卵巢和睾丸中 PRLR 的表达水平显着高于春季和秋季，而夏季和冬季个体的 FSH 和 LH 血清浓度显着低于春季和冬季个体。秋天。下丘脑、卵巢和睾丸中的 PRLR 表达水平与 FSH 和 LH 血清浓度呈负相关，说明 PRLR 可能负调节季节性生殖活动。PRLR在卵巢和睾丸中的表达水平显着高于下丘脑水平，提示PRLR对性腺的调节作用可能显着高于下丘脑。此外，与男性相比，女性下丘脑和性腺春季、夏季、秋季和冬季的 PRLR 表达水平显着高于男性，表明 PRLR 的调节作用可能具有性别依赖性。综上所述，本研究有助于深入了解条纹仓鼠的季节性调节繁殖机制，合理控制种群丰度。PRLR在卵巢和睾丸中的表达水平显着高于下丘脑水平，提示PRLR对性腺的调节作用可能显着高于下丘脑。此外，与男性相比，女性下丘脑和性腺春季、夏季、秋季和冬季的 PRLR 表达水平显着高于男性，表明 PRLR 的调节作用可能具有性别依赖性。综上所述，本研究有助于深入了解条纹仓鼠的季节性调节繁殖机制，合理控制种群丰度。PRLR在卵巢和睾丸中的表达水平显着高于下丘脑水平，提示PRLR对性腺的调节作用可能显着高于下丘脑。此外，与男性相比，女性下丘脑和性腺春季、夏季、秋季和冬季的 PRLR 表达水平显着高于男性，表明 PRLR 的调节作用可能具有性别依赖性。综上所述，本研究有助于深入了解条纹仓鼠的季节性调节繁殖机制，合理控制种群丰度。与男性相比，女性下丘脑和性腺春季、夏季、秋季和冬季的 PRLR 表达水平显着高于男性，表明 PRLR 的调节作用可能具有性别依赖性。综上所述，本研究有助于深入了解条纹仓鼠的季节性调节繁殖机制，合理控制种群丰度。与男性相比，女性下丘脑和性腺春季、夏季、秋季和冬季的 PRLR 表达水平显着高于男性，表明 PRLR 的调节作用可能具有性别依赖性。综上所述，本研究有助于深入了解条纹仓鼠的季节性调节繁殖机制，合理控制种群丰度。