The purpose of this review was to quantitatively synthesize studies using acceptance and commitment therapy (ACT) with individuals with neurodevelopmental disorders (NNDs), their parents, and staff members that support them. Thirty studies published in peer-reviewed journals between 2006 and 2020 met inclusion criteria. They were reviewed and coded on variables associated with participants’ characteristics, settings, dropouts, design type, ACT procedures and measures, social validity, treatment integrity, and main findings. The What Works Clearinghouse (WWC), the revised Cochrane risk-of-bias tool for randomized trials (RoB2) and the Risk of Bias in Nonrandomized Studies of Interventions (ROBINS-I) were applied to evaluate the quality of the studies. Results indicated that 20 studies used group designs and 10 studies used single-case designs. Participants with NNDs consisted predominantly of those with autism spectrum disorder, attention deficit hyperactivity disorder, and learning disabilities. Group studies reported process and outcome measures exclusively; whereas, single-case studies also incorporated behavioral/direct measures. Overall, results showed mixed improvements across studies using indirect and direct measures. Lastly, quality assessment for group studies presented moderate or serious risk of bias and two single-case studies did not meet WWC evidence of effectiveness. Directions for future research and practice are discussed.

本综述的目的是定量综合使用接受和承诺疗法 (ACT) 对患有神经发育障碍 (NND) 的个体、他们的父母和支持他们的工作人员的研究。2006 年至 2020 年间在同行评审期刊上发表的 30 项研究符合纳入标准。他们对与参与者的特征、环境、辍学、设计类型、ACT 程序和措施、社会效度、治疗完整性和主要发现相关的变量进行了审查和编码。What Works Clearinghouse (WWC)、修订后的 Cochrane 随机试验偏倚风险工具 (RoB2) 和非随机干预研究中的偏倚风险 (ROBINS-I) 用于评估研究质量。结果表明，20 项研究使用了小组设计，10 项研究使用了单例设计。患有 NND 的参与者主要包括患有自闭症谱系障碍、注意力缺陷多动障碍和学习障碍的人。小组研究仅报告过程和结果测量；然而，单一案例研究也纳入了行为/直接措施。总体而言，结果显示，使用间接和直接措施的研究的改进参差不齐。最后，小组研究的质量评估存在中度或严重的偏倚风险，两项单例研究不符合 WWC 的有效性证据。讨论了未来研究和实践的方向。单一案例研究也纳入了行为/直接措施。总体而言，结果显示，使用间接和直接措施的研究的改进参差不齐。最后，小组研究的质量评估存在中度或严重的偏倚风险，两项单例研究不符合 WWC 的有效性证据。讨论了未来研究和实践的方向。单一案例研究也纳入了行为/直接措施。总体而言，结果显示，使用间接和直接措施的研究的改进参差不齐。最后，小组研究的质量评估存在中度或严重的偏倚风险，两项单例研究不符合 WWC 的有效性证据。讨论了未来研究和实践的方向。