An efficient and general synthetic route of deuterium-labeled phthalate esters is described with high isotopic enrichment and excellent chemical purities using inexpensive and readily available o-xylene-D₁₀ as labeled starting material. The structures and isotope-abundance were confirmed via ¹H NMR and mass spectrometry. These deuterium labeled phthalate esters can be used as analytical reference standards for the detection of plasticizer residues in soil, water, food, plastic products, etc.

中文翻译：

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一种合成稳定同位素氘标记邻苯二甲酸酯的高效通用方法

使用廉价且容易获得的邻二甲苯-D ₁₀作为标记的起始材料，描述了一种高效且通用的氘标记邻苯二甲酸酯合成路线，具有高同位素富集和优异的化学纯度。结构和同位素丰度通过¹ H NMR 和质谱确认。这些氘标记的邻苯二甲酸酯可作为分析参考标准，用于检测土壤、水、食品、塑料制品等中的增塑剂残留。