Low-molecular-weight organic acids that generally contain one to three carboxyl groups are involved in many important biological processes; therefore, it is important to develop a quantitative method for analyzing organic acids in serum in order to allow an evaluation of metabolic changes. In this study, we evaluated a protocol for detecting 26 organic acids in serum based on ultrasound-assisted derivatization by gas chromatography/mass spectrometry (GC/MS).

中文翻译：

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人血清中有机酸谱的气相色谱/质谱分析：直接超声辅助衍生化方案

通常含有一到三个羧基的低分子量有机酸参与了许多重要的生物过程；因此，重要的是开发一种定量分析血清中有机酸的方法，以便评估代谢变化。在本研究中，我们评估了基于超声辅助衍生的气相色谱/质谱 (GC/MS) 检测血清中 26 种有机酸的方案。