Antimicrobial resistance is widely studied and well-characterized from a clinical perspective. However, considerably less information is available regarding resistance in environmental settings, especially in aquatic habitats. This study presents data regarding the occurrence, distribution and the antimicrobial susceptibility profile of bacteria isolated from Guanabara Bay (GB), a heavily polluted tropical urban estuary and an important tourist attraction in Rio de Janeiro, Brazil. Water samples from sites characterized by growing degrees of pollution were analysed by culture-dependent methods, revealing the presence of multidrug-resistant bacteria and clinically relevant indicators of antimicrobial resistance, such as extended-spectrum beta-lactamases. Isolates were identified by mass spectrometry, which indicated the presence of potential human pathogens such as Aeromonas spp. and Vibrio spp. Bacteria harbouring beta-lactam resistance genes were also detected. Although GB is widely used as a recreational and fishing area, there is a substantial knowledge gap regarding the monitoring of antimicrobial resistance and the risk that exposure to these waters poses to public health. Thus, this study reveals new information that calls for better comprehension of antimicrobial resistance in aquatic environments, especially those used for recreational purposes.

中文翻译：

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潜入未知：热带城市河口抗菌素耐药性热点的识别

从临床角度来看，抗菌素耐药性已得到广泛研究和充分表征。然而，关于环境环境，尤其是水生栖息地中的抗性的可用信息要少得多。本研究提供了有关从瓜纳巴拉湾 (GB) 中分离出的细菌的发生、分布和抗菌敏感性概况的数据，瓜纳巴拉湾是巴西里约热内卢的一个严重污染的热带城市河口和一个重要的旅游景点。来自污染程度不断增加的地点的水样通过依赖培养的方法进行分析，揭示了多重耐药菌的存在和临床相关的抗菌素耐药性指标，如超广谱β-内酰胺酶。通过质谱法鉴定分离物，气单胞菌属 和弧菌属。还检测到含有β-内酰胺抗性基因的细菌。尽管 GB 被广泛用作休闲和捕鱼区，但在监测抗菌素耐药性和暴露于这些水域对公众健康构成的风险方面存在巨大的知识差距。因此，这项研究揭示了新信息，要求更好地理解水生环境中的抗菌素耐药性，尤其是那些用于娱乐目的的环境。