Vulvovaginal candidiasis (CVV) is a condition in which signs and symptoms are related to inflammation caused by Candida spp infection. It is the second leading cause of vaginitis in the world, representing a public health problem. The present systematic review comes with the proposal of analyze and identify the available evidence on CVV prevalence in Brazil, pointing out its variability by regions. For this, a systematic literature review was carried out with meta-analysis of cross-sectional and cohort studies, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guide recommendations, and was registered in the International Prospective Register of Systematic Reviews (PROSPERO 2020 CRD42020181695). The databases used for survey were LILACS, Scielo, Scopus, PUBMED, Web of Science and CINAHL. Fifteen studies were selected to estimate CVV prevalence in the Brazilian territory. South and Southeast regions have higher prevalences than the North and Northeast regions, no data were found for the Midwest region. The estimated prevalence for Brazil is 18%, however, it is suggested that this number is higher due to underreporting and the presence of asymptomatic cases. Therefore, new epidemiological studies are recommended throughout Brazil, to elucidate the profile of this disease in the country, in addition to assisting in the elaboration of an appropriate prevention plan by state. Lay summary Data found in the literature regarding the epidemiological profile of vulvovaginal candidiasis in Brazil are obsolete and incomplete, so the present systematic review has the proposal to analyze and identify the evidence on vulvovaginal candidiasis prevalence in Brazil. The estimated prevalence is 18%; however, this number can be higher.

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巴西外阴阴道念珠菌病的患病率：系统评价

外阴阴道念珠菌病 (CVV) 是一种症状和体征与念珠菌感染引起的炎症有关的疾病。它是世界上阴道炎的第二大原因，代表了一个公共卫生问题。本系统评价提出了分析和确定巴西 CVV 流行率的现有证据的建议，并指出其因地区而异。为此，根据系统评价和荟萃分析的首选报告项目 (PRISMA) 指南建议，对横断面和队列研究进行荟萃分析，进行系统文献综述，并在国际系统前瞻性登记册中注册评论（PROSPERO 2020 CRD42020181695）。用于调查的数据库是 LILACS、Scielo、Scopus、PUBMED、Web of Science 和 CINAHL。选择了 15 项研究来估计巴西境内的 CVV 流行率。南部和东南部地区的患病率高于北部和东北部地区，中西部地区没有发现数据。巴西的估计患病率为 18%，然而，由于报告不足和无症状病例的存在，这一数字被认为更高。因此，建议在巴西进行新的流行病学研究，以阐明该疾病在该国的概况，并协助各州制定适当的预防计划。总结 文献中关于巴西外阴阴道念珠菌病流行病学概况的数据已过时且不完整，因此，本系统评价建议分析和确定巴西外阴阴道念珠菌病流行的证据。估计患病率为 18%；但是，这个数字可能更高。