Airway gene expression identifies subtypes of type 2 inflammation in severe asthma,Clinical & Experimental Allergy

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Airway gene expression identifies subtypes of type 2 inflammation in severe asthma
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2021-06-17 , DOI: 10.1111/cea.13966
Laurits Frøssing _{1,

2} , Alexander Silberbrandt _{1,

2} , Anna Von Bülow ₁ , Ditte Kjaersgaard Klein _{1,

2} , Marcus Ross Christensen ₁ , Vibeke Backer ₃ , Katherine J Baines ₄ , Celeste Porsbjerg _{1,

2}

Affiliation

Type 2 inflammation is characterized by enhanced activity of interleukin (IL)-4, -5 and -13, and treatments targeting these pathways are available for treatment of severe asthma. At present, the pattern of pathway activity and the implications overlapping of pathway activity are unknown.

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