Objectives: Mood disorders are commonly associated with attention-deficit/hyperactivity disorder (ADHD), adding to the clinical complexity. Some symptoms associated with ADHD are often associated with an increase in emotional disorders and depression. Hence, the management of comorbid mood symptoms in the context of ADHD represents a particularly difficult clinical challenge. Few studies in literature, and probably none in the Arab world, have investigated the impact of individual common comorbid disorders on the efficacy of atomoxetine (a nonstimulant norepinephrine reuptake inhibitor) as a monotherapy for the treatment of these comorbid mood symptoms. Therefore, our aim was to investigate the effect of atomoxetine in a sample of drug-naive Egyptian children with ADHD, with and without comorbid mood disorders.

中文翻译：

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托莫西汀在患有和不患有共存情绪障碍的儿童注意力缺陷/多动障碍中的作用

目的：情绪障碍通常与注意力缺陷/多动障碍 (ADHD) 相关，增加了临床复杂性。与 ADHD 相关的一些症状通常与情绪障碍和抑郁症的增加有关。因此，在 ADHD 背景下的共病情绪症状的管理代表了一个特别困难的临床挑战。很少有文献研究，可能在阿拉伯世界也没有研究过个体常见共病对托莫西汀（一种非刺激性去甲肾上腺素再摄取抑制剂）作为治疗这些共病情绪症状的单一疗法的疗效的影响。因此，我们的目的是研究托莫西汀对患有 ADHD 的未使用药物的埃及儿童样本的影响，这些儿童患有或不患有共存的情绪障碍。