To determine whether a community-based physical rehabilitation program could improve the prognosis of patients who had undergone percutaneous coronary intervention after acute myocardial infarction, we randomly divided 164 consecutive patients into 2 groups of 82 patients. Patients in the rehabilitation group underwent 3 months of supervised exercise training, then 9 months of community-based, self-managed exercise; patients in the control group received conventional treatment. The primary endpoint was major adverse cardiac events (MACE) during the follow-up period (25 ± 15.4 mo); secondary endpoints included left ventricular ejection fraction, 6-minute walk distance, and laboratory values at 12-month follow-up.

During the study period, the incidence of MACE was significantly lower in the rehabilitation group (13.4% vs 24.4%; P <0.01). Cox proportional hazards regression analysis indicated a significantly lower risk of MACE in the rehabilitation group (hazard ratio=0.56; 95% CI, 0.37–0.82; P=0.01). At 12 months, left ventricular ejection fraction and 6-minute walk distance in the rehabilitation group were significantly greater than those in the control group (both P <0.01), and laboratory values also improved.

These findings suggest that community-based physical rehabilitation significantly reduced MACE risk and improved cardiac function and physical stamina in patients who underwent percutaneous coronary intervention after acute myocardial infarction.

为了确定基于社区的物理康复计划是否可以改善急性心肌梗死后接受经皮冠状动脉介入治疗的患者的预后，我们将 164 名连续患者随机分为 2 组，每组 82 名患者。康复组患者接受了 3 个月的有监督运动训练，然后进行了 9 个月的以社区为基础的自我管理运动；对照组患者接受常规治疗。主要终点是随访期间（25±15.4 个月）的主要不良心脏事件（MACE）；次要终点包括左心室射血分数、6 分钟步行距离和 12 个月随访时的实验室值。

研究期间，康复组MACE发生率显着降低（13.4% vs 24.4%；P <0.01）。Cox 比例风险回归分析表明，康复组的 MACE 风险显着降低（风险比 = 0.56；95% CI，0.37-0.82；P = 0.01）。12个月时，康复组左心室射血分数和6分钟步行距离明显大于对照组（均P <0.01），实验室值也有所改善。

这些研究结果表明，以社区为基础的身体康复显着降低了急性心肌梗死后接受经皮冠状动脉介入治疗的患者的 MACE 风险，并改善了心脏功能和体能。