Kampo medicines contain many kinds of herbal drugs. Chinpi and Kippi, dried citrus peels, are components of a substantial number of Kampo medicine. They contain abundant flavonoids and studies on hesperidin, narirutin, and nobiletin as active ingredient have been conducted. Conversely, in Kagoshima prefecture, located in the southwestern part of the Japanese Islands, various citrus products are cultivated. Among them, Tankan and Daimasaki are specialies. In this study, we conducted high- performance liquid chromatography to determine the difference in flavonoid contents among Tankan, Daimasaki, Tankan related product, Chinpi, and Kippi. As a result, several active components, such as hesperidin, narirutin, nobiletin, and tangeretin, in common with crude drug, Chinpi, were detected in local citrus fruits. In addition, some active components little or not found in Chinpi, for example hesperetin and rutin, were detected in the local products. A detailed analysis of active components considering their genetic origin, the time of fruit collection, and different parts of the fruit used (peel, albedo, edible parts, and the whole) will need to be discussed to get the most out of the citrus fruits or make best use of them for health and longevity.

汉方药含有多种草药。Chinpi 和 Kippi，即干柑橘皮，是大量汉方药的成分。它们含有丰富的类黄酮，并已对橙皮苷、narirutin 和 nobiletin 作为活性成分进行了研究。相反，在日本列岛西南部的鹿儿岛县，种植了各种柑橘产品。其中，短观和大正是特产。在本研究中，我们进行了高效液相色谱，以确定短观、大正、短观相关产品、Chinpi 和 Kippi 之间的类黄酮含量差异。结果，在当地柑橘类水果中检测到与生药金皮相同的几种活性成分，如橙皮苷、narirutin、nobiletin和橘子素。此外，在土特产品中检测到一些在金皮中很少或没有发现的活性成分，例如橙皮素和芦丁。需要讨论活性成分的详细分析，考虑其遗传来源、水果采集时间和所用水果的不同部分（果皮、反照率、可食用部分和整体），以充分利用柑橘类水果或充分利用它们来促进健康和长寿。