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Cell and molecular toxicity of lanthanum nanoparticles: are there possible risks to humans?
Nanotoxicology ( IF 5 ) Pub Date : 2021-06-18 , DOI: 10.1080/17435390.2021.1940340
Amir Mohammad Malvandi 1 , Sara Shahba 2 , Abbas Mohammadipour 3 , Seyed Hamidreza Rastegar-Moghaddam 3 , Mahmoud Abudayyak 4
Affiliation  

Abstract

Lanthanum nanoparticles are widely used in industry, agriculture, and biomedicine. Over 900 kg of lanthanum is annually released into the environment only in Europe, 50 times higher than the metals, mercury, and cadmium’s environmental spread. Human health risk associated with long-term exposure to the abundant lanthanum nanoparticles is a concerning environmental issue. Due to lanthanum’s ability to disrupt the main biological barriers and interrupt various cells’ hemostasis, they seem to cause severe disruptions to various tissues. This review opens a new perspective regarding the cellular and molecular interaction of nanosized and ionic lanthanum with the possible toxicity on the nervous system and other tissues that would show lanthanum nanoparticles’ potential danger to follow in toxicological science.



中文翻译:

镧纳米粒子的细胞和分子毒性:对人类是否可能存在风险?

摘要

镧纳米粒子广泛应用于工业、农业和生物医学。仅在欧洲,每年就有超过 900 公斤的镧被释放到环境中,比金属、汞和镉的环境扩散高出 50 倍。与长期暴露于丰富的镧纳米粒子相关的人类健康风险是一个令人担忧的环境问题。由于镧具有破坏主要生物屏障和中断各种细胞止血的能力,它们似乎对各种组织造成严重破坏。这篇综述为纳米级和离子镧的细胞和分子相互作用以及对神经系统和其他组织的可能毒性开辟了新的视角,这将表明镧纳米粒子在毒理学科学中的潜在危险。

更新日期:2021-06-18
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