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Pityriacitrin marine alkaloids as novel antiviral and anti-phytopathogenic-fungus agents
Pest Management Science ( IF 4.1 ) Pub Date : 2021-06-16 , DOI: 10.1002/ps.6510
Tie-Nan Wang 1 , Shan Yang 1 , Shao-Yang Shi 1 , Wen-Ying Yuan 1 , Jian-Xin Chen 1 , Zhong-Yu Duan 1 , Ai-Dang Lu 1 , Zi-Wen Wang 2 , Qing-Min Wang 3
Affiliation  

Plant diseases have been gripping agricultural production, seriously affecting the growth and yields of crops. Marine natural products are an important source for novel drugs discovery. In this work, pityriacitrin marine alkaloids were selected as the parent structures. A series of pityriacitrin alkaloid analogues were rationally designed, synthesized and evaluated for their antiviral activities and fungicidal activities.

中文翻译:

Pityriacitrin 海洋生物碱作为新型抗病毒和抗植物病原真菌剂

植物病害一直困扰着农业生产,严重影响农作物的生长和产量。海洋天然产物是新药发现的重要来源。在这项工作中,选择糠酸苷海洋生物碱作为母体结构。合理设计、合成并评价了一系列糠秕菌素类生物碱类似物的抗病毒活性和杀菌活性。
更新日期:2021-06-16
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