During neuronal diseases, neuronal proteins get disturbed due to changes in the connections of neurons. As a result, neuronal proteins get disturbed and cause epilepsy. At the genetic level, many mutations may take place in proteins like axon guidance proteins, leucine-rich glioma inactivated 1 protein, microtubular protein, pore-forming, chromatin remodeling, and chemokine proteins which may lead toward temporal lobe epilepsy. These proteins can be targeted in the future for the treatment purpose of epilepsy. Novel avenues can be developed for therapeutic interventions by these new insights.

中文翻译：

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颞叶癫痫：我们对蛋白质改变的理解是什么？

在神经元疾病期间，神经元蛋白质会因神经元连接的变化而受到干扰。结果，神经元蛋白质受到干扰并导致癫痫。在基因水平上，许多突变可能发生在蛋白质中，例如轴突引导蛋白、富含亮氨酸的神经胶质瘤灭活 1 蛋白、微管蛋白、成孔、染色质重塑和趋化因子蛋白，这些蛋白可能导致颞叶癫痫。这些蛋白质将来可以作为治疗癫痫的目标。通过这些新的见解，可以为治疗干预开辟新的途径。