Research productivity and outcomes of junior researchers are usually correlated with the degree and quality of mentorship they receive. A bottom-up approach was followed to develop a research group at the Ocean Road Cancer Institute (ORCI), the major cancer center in Tanzania, to build upon the existing clinical and research resources and institutional global collaborations. The ORCI is a clinical center focused on radio- and chemo-therapy treatment of cancer patients from all over Tanzania. In addition, ORCI has a long-standing early detection program for educating women and screening them for cervical cancer. The ORCI physicians have been exposed to cancer research for the past 20 years through non-degree and degree training in the USA and Europe. In addition, US and European groups have been conducting collaborative research and training of oncologists and graduate students at ORCI. The exposure to research through the above-listed venues motivated the clinicians at ORCI to develop their own Research Club (RC) to learn about research methods, seek independent funding, and outline a research agenda for cancer research in Tanzania. However, it seems that mentorship is needed to help the RC members apply the lessons learned from didactic teaching. Mentorship is also needed to enable the RC members to utilize the enormous clinical and epidemiologic data generated by the institutional programs for prevention, treatment, and follow up of patients. This manuscript describes the inception of the program and its achievements, limitations, and suggested opportunities for improvement as a possible model for other LMICs.

初级研究人员的研究生产力和成果通常与他们接受指导的程度和质量相关。遵循自下而上的方法，在坦桑尼亚的主要癌症中心大洋路癌症研究所 (ORCI) 建立了一个研究小组，以利用现有的临床和研究资源以及机构全球合作。ORCI 是一个临床中心，专注于对来自坦桑尼亚各地的癌症患者进行放射和化学治疗。此外，ORCI 有一项长期的早期检测计划，用于教育女性并筛查宫颈癌。在过去的 20 年里，ORCI 医生通过在美国和欧洲的非学位和学位培训接触了癌症研究。此外，美国和欧洲的团体一直在 ORCI 对肿瘤学家和研究生进行合作研究和培训。通过上述场所接触研究促使 ORCI 的临床医生发展自己的研究俱乐部 (RC)，以了解研究方法、寻求独立资金并概述坦桑尼亚癌症研究的研究议程。然而，似乎需要指导来帮助 RC 成员应用从教学中学到的经验教训。还需要指导，使 RC 成员能够利用机构项目产生的大量临床和流行病学数据，用于患者的预防、治疗和随访。这份手稿描述了该计划的开始及其成就、局限性、