In this issue of Chem, Zhou and co-workers report a new strategy for synthesizing optically active N–C axially chiral compounds. In the presence of a chiral norbornene-ester-Pd catalyst, the Catellani reaction of iodobenzene derivatives with N-(2-substituted-phenyl)-2-bromobenzamides proceeds in a highly enantioselective manner to give N–C axially chiral N-aryl-phenanthridinone derivatives.

中文翻译：

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一种独特的高对映选择性合成 N-C 轴向手性化合物的方法

在本期Chem 中，Zhou 和同事报告了一种合成光学活性 N-C 轴向手性化合物的新策略。在手性降冰片烯-酯-Pd催化剂存在下，碘苯衍生物与N- (2-取代-苯基)-2-溴苯甲酰胺的Catellani反应以高度对映选择性的方式进行，得到N-C轴向手性N-芳基-菲啶酮衍生物。