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Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves
Pharmaceutical Chemistry Journal ( IF 0.9 ) Pub Date : 2021-06-15 , DOI: 10.1007/s11094-021-02407-y
A. K. Whaley , A. O. Ponkratova , A. A. Orlova , E. B. Serebryakov , S. N. Smirnov , P. Proksh , N. S. Ionov , V. V. Poroikov , V. G. Luzhanin

Phytochemical analysis of cloudberry leaves isolated one new (1) and four well-known compounds (2-5) and established their structures. Compounds 1 (4-O-α-L-arabinofuranosylellagic acid) and 2 [(–)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavonoid glucuronic glycosides quercetin 3-O-β-D-glucuronide (3), quercetin 3-O-β-D-2′′-galloylglucuronide (4), and kaempferol 3-O-β-D-glucuronide (5). Compounds 4 and 5 were isolated from Rubus chamaemorus L. for the first time. Predictions of the biological activity spectra for isolated 1-5 using the PASS program provided insights regarding the most promising directions for studying their biological activity.



中文翻译:

云莓 (Rubus Chamaemorus L.) 叶中多酚次生代谢物的植物化学分析

云莓叶的植物化学分析分离出一种新化合物 ( 1 ) 和四种众所周知的化合物 ( 2 - 5 ) 并确定了它们的结构。化合物1 (4- O -α- L -arabinofuranosylellagic acid) 和2 [(-)-表儿茶素] 属于单宁类。分离的化合物的其余的类黄酮苷葡糖醛槲皮素-3- ö -β- d葡萄糖醛酸苷(3),槲皮素-3- ö -β- d -2'' - galloylglucuronide(4),山奈酚3- ö -β - D -葡糖苷酸 ( 5)。化合物45为首次从Rubus chamaemorus L.中分离得到。生物活性谱的预测为孤立1 - 5使用提供了有关为研究其生物活性最有前途的方向的见解PASS计划。

更新日期:2021-06-15
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