A series of thermoresponsive polyacrylamides containing sulfide, sulfone, or sulfoxide was successfully prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. The thermal properties of polyacrylamides with sulfone or sulfoxide, which have not been studied before, were investigated for the first time. While poly[N-(2-(propylsulfonyl)ethyl)acrylamide] (P2SO2) with sulfone groups was water insoluble, poly[N-(2-(propylsulfinyl)ethyl)acrylamide] (P2SO) with sulfoxide groups was water soluble, indicating that the sulfoxide moiety is more hydrophilic than sulfone. By controlling the end of the polymer chain, we synthesized poly[N-(2-(ethylsulfonyl)ethyl)acrylamide] (P1SO2) and poly[N-(2-(butylsulfinyl)ethyl)acrylamide] (P3SO), which exhibit an lower critical solution temperature (LCST) in water around 24–26°C. For adjusting a wide range of LCST, we synthesized the random copolymers by controlling the initial feed ratio of hydrophobic M2SO2 and hydrophilic M2SO. The amphiphilic block copolymers were also synthesized and assembled in water to yield the micelles. After adding H₂O₂ to this micellar solution, the hydrophobic block was oxidized and converted to a hydrophilic block, leading to the transformation of micelles to unimers.

中文翻译：

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热敏性含砜和亚砜的聚丙烯酰胺

通过可逆加成-断裂链转移（RAFT）聚合反应成功制备了一系列含有硫化物、砜或亚砜的热响应聚丙烯酰胺。首次研究了以前没有研究过的含有砜或亚砜的聚丙烯酰胺的热性能。虽然聚[ ñ - （2-（丙基磺酰基）乙基）丙烯酰胺]（P2SO2）与砜基团是不溶于水，聚[ Ñ - （2-（丙基亚磺酰基）乙基）丙烯酰胺]（P2SO）与亚砜基团是水溶性的，指示亚砜部分比砜更具亲水性。通过控制聚合物链的末端，我们合成了聚[ N- (2-(乙基磺酰基)乙基)丙烯酰胺](P1SO2)和聚[ N-(2-(丁基亚磺酰基)乙基)丙烯酰胺] (P3SO)，其在水中的临界溶解温度 (LCST) 较低，约为 24–26°C。为了调整大范围的 LCST，我们通过控制疏水 M2SO2 和亲水 M2SO 的初始进料比合成了无规共聚物。两亲嵌段共聚物也被合成并在水中组装以产生胶束。在该胶束溶液中加入 H ₂ O _{2 后}，疏水性嵌段被氧化并转化为亲水性嵌段，导致胶束转化为单体。