This study investigated the effect of an organic pollutant (Bisphenol- A, an endocrine-disrupting chemical) on the stability of a mixture of nanoparticles (NPs). Experiments were conducted in seawater chemistry condition with TiO₂/ZnO NP concentration ratio: 0.01, 0.1, 1, 10,100; pH: 7.4 and 8.1; BPA concentration: 1 and 10 μg/L. The presence of BPA was found to increase the size of NP. Lower pH of 7.4 increased size of NPs from 3 to 297% (at 1 μg/L BPA; NP ratio = 0.1 to 100). Aggregation rate constant values ranged between 0.17 and 1.81 nm/s in pH 7.4 suspension and between 0.48 and 56 nm/s in pH 8.1 suspension. Factors, such as pH and NP mass concentration had major effects on size change for suspension having the same ratio of TiO₂/ZnO. NP aggregate was comprised of 97% ZnO NP, 3% TiO₂ NP and had 1.39 mg/kg BPA. Overall, this study found dominance of van der Waals forces of attraction in mixture suspension of NPs and BPA. The obtained result on NP persistence in seawater can now be used in estimating exposure doses of a mixture of nanoparticles during inadvertent exposure.

本研究调查了有机污染物（双酚 A，一种内分泌干扰化学品）对纳米颗粒 (NP) 混合物稳定性的影响。实验在海水化学条件下进行，TiO ₂ /ZnO NP浓度比为：0.01、0.1、1、10,100；pH值：7.4和8.1；BPA 浓度：1 和 10 μg/L。发现 BPA 的存在会增加 NP 的大小。7.4 的较低 pH 值将 NP 的大小从 3% 增加到 297%（在 1 μg/L BPA 下；NP 比率 = 0.1 到 100）。聚集速率常数值在 pH 7.4 悬浮液中介于 0.17 和 1.81 nm/s 之间，在 pH 8.1 悬浮液中介于 0.48 和 56 nm/s 之间。pH和NP质量浓度等因素对具有相同TiO ₂比例的悬浮液的尺寸变化有主要影响/氧化锌。NP 聚集体由 97% ZnO NP、3% TiO ₂ NP 和 1.39 mg/kg BPA 组成。总的来说，这项研究发现在 NPs 和 BPA 的混合悬浮液中，范德华引力占主导地位。获得的关于 NP 在海水中的持久性的结果现在可用于估计无意暴露期间纳米颗粒混合物的暴露剂量。