Depressive disorder is a major psychiatric illness, and a disturbed brain-gut-microbiome axis may contribute to its pathophysiology. Chronic Helicobacter pylori (H. pylori) infections are common in the general population and using multiple antibiotics is required for its eradication, which is associated with gut dysbiosis and may lead to depression. We aimed to evaluate the risk of psychiatrist-diagnosed depression in patients with peptic ulcer diseases (PUD) receiving anti-H. pylori therapy.

中文翻译：

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根除幽门螺杆菌后短期抑郁症的风险增加：一项基于人群的嵌套队列研究

抑郁症是一种主要的精神疾病，脑-肠-微生物组轴紊乱可能导致其病理生理学。慢性幽门 螺旋杆菌（ħ。 幽门）感染在一般人群中是常见的，使用多种抗生素需要将其消灭，这是与肠生态失调相关联，并且可能会导致抑郁症。我们旨在评估接受抗H治疗的消化性溃疡病 (PUD) 患者发生精神科医生诊断的抑郁症的风险。 幽门螺旋杆菌疗法。