Noninvasive detection of Helicobacter pylori plays an important role in clinical practice. However, few noninvasive methods have been applied in epidemiological studies due to the requirement for expensive equipment and complicated processes. The aim of this study was to establish a reliable, fast, and inexpensive noninvasive method based on CRISPR-Cas12a technology for the detection of Helicobacter pylori in stool specimens.

中文翻译：

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基于 CRISPR 的粪便样本中幽门螺杆菌检测

幽门螺杆菌的无创检测在临床实践中发挥着重要作用。然而，由于需要昂贵的设备和复杂的过程，很少有非侵入性方法应用于流行病学研究。本研究的目的是建立一种基于 CRISPR-Cas12a 技术的可靠、快速且廉价的无创方法，用于检测粪便标本中的幽门螺杆菌。