Prenatal stress is associated with increased susceptibility to psychiatric and metabolic disorders later in life. Prenatal exposure to stress mediators may have sex-dependent effects on offspring brain and metabolic function, promoting a sex-specific vulnerability to psychopathology and metabolic alterations at adulthood. In this work, the impact of prenatal stress on glucose homeostasis and peripheral metabolism of male and female offspring was investigated in a chronic anxiety animal model.

中文翻译：

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产前压力引起的慢性焦虑模型中外周代谢的性别特异性变化

产前压力与生命后期对精神和代谢疾病的易感性增加有关。产前暴露于压力介质可能对后代的大脑和代谢功能产生性别依赖性影响，从而促进成年期对精神病理学和代谢改变的性别特异性易感性。在这项工作中，在慢性焦虑动物模型中研究了产前压力对雄性和雌性后代葡萄糖稳态和外周代谢的影响。