Hepatocellular carcinoma (HCC) is the most common type of liver cancer. The effectiveness of treatment depends on detection in its early stages. The aim of this study is to fabricate an HCC liver dynamic phantom with tissue-mimicking materials for magnetic resonance imaging. Three gelatin phantoms with concentrations of 2.5%, 4.0%, and 5.0 wt% were made. All phantoms contained three main materials; hydroxyethyl cellulose as gelling agent; benzalkonium chloride as antibacterial agent; and propanediol as a solvent. Three samples of glycerol and agarose were made in three different sizes (2.0, 1.0, and 0.5 cm) to represent HCC samples. The chemical, mechanical (density and compression strength), electrical conductivity, and imaging properties of all three phantoms were studied over a period of six weeks. Dynamic contrast enhancement (DCE) was applied to study the HCC pattern. The chemical properties of the three phantoms are uniform. Density was stable for all phantom concentrations and of course was lowest in concentration 2.5 wt%. The change observed in T₁ over six weeks was 8.15%, 13.07% and 9.98%, while the change in T₂ was 12.37%, 19.40% and 10.27% in the concentrations of 2.5, 4.0 and 5.0 wt%, respectively. HCC samples behaved in a typical pattern after application of DCE and the smallest detection size using the Dixon sequence was 1 cm. The study succeeded in fabricating HCC with a dynamic phantom of the liver with the application of DCE on HCC in different stages.

肝细胞癌（HCC）是最常见的肝癌类型。治疗的有效性取决于早期发现。本研究的目的是使用组织模拟材料制作用于磁共振成像的 HCC 肝脏动态模型。制备了三个浓度分别为 2.5%、4.0% 和 5.0% 的明胶体模。所有幻影都包含三种主要材料；羟乙基纤维素作胶凝剂；苯扎氯铵作为抗菌剂；和丙二醇作为溶剂。制备了三种不同尺寸（2.0、1.0 和 0.5 cm）的甘油和琼脂糖样品，以代表 HCC 样品。在六周的时间内研究了所有三个体模的化学、机械（密度和压缩强度）、导电性和成像特性。应用动态对比度增强 (DCE) 来研究 HCC 模式。三个体模的化学性质是一致的。密度对于所有体模浓度都是稳定的，当然浓度最低为 2.5 wt%。在 T 中观察到的变化₁超过六周为 8.15%、13.07% 和 9.98%，而在2.5、4.0 和 5.0 wt% 的浓度下，T ₂的变化_分别为 12.37%、19.40% 和 10.27%。HCC 样品在应用 DCE 后表现出典型模式，使用 Dixon 序列的最小检测尺寸为 1 cm。该研究将 DCE 应用于不同阶段的 HCC，成功地制造了具有动态肝脏模型的 HCC。