Adrenal suppression (AS), a potential side effect of glucocorticoid therapy (including inhaled corticosteroids), can be associated with significant morbidity and even death. In Canada, adrenal crisis secondary to AS continues to be reported in children. Being aware of symptoms associated with AS, understanding the risk factors for developing this condition, and familiarity with potential strategies to reduce risks associated with AS, are essential starting points for any clinician prescribing glucocorticoids.

中文翻译：

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外源性糖皮质激素的肾上腺抑制：识别危险因素和预防发病率

肾上腺抑制 (AS) 是糖皮质激素治疗（包括吸入皮质类固醇）的潜在副作用，可能与显着的发病率甚至死亡有关。在加拿大，继发于 AS 的肾上腺危象在儿童中继续出现。了解与 AS 相关的症状、了解发生这种情况的风险因素以及熟悉降低与 AS 相关风险的潜在策略是任何临床医生开具糖皮质激素处方的重要起点。