Abstract High intake of over-the-counter, non-steroidal anti-inflammatory drugs, such as ibuprofen, has resulted in their presence in wastewaters and surface waters. The potentially harmful effect of ibuprofen present in the waters has led to a search for new methods of drugs’ removal from the environment. One of the most important technological and economical solutions comprises microbiological degradation of these resistant pollutants. Searching for new strains able to degrade ibuprofen could be one of the answers for increasing the detection of pharmaceuticals in the waters. In this study, the ability of bacterial strain Bacillus thuringiensis B1(2015b) to remove ibuprofen is described. Bacteria were cultured in both monosubstrate and cometabolic systems with 1, 3, 5, 7 and 9 mg L-1 ibuprofen and 1 g L-1 glucose as a carbon source. Bacillus thuringiensis B1(2015b) removed ibuprofen up to 9 mg L-1 in 232 hours in the monosubstrate culture, whereas in the cometabolic culture the removal of the drug was over 6 times faster. That is why the examined strain could be used to enhance the bioremediation of ibuprofen.

中文翻译：

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芽孢杆菌对布洛芬的生物降解动力学。B1(2015b)

摘要 大量摄入非处方非甾体抗炎药，如布洛芬，导致它们存在于废水和地表水中。布洛芬存在于水中的潜在有害影响促使人们寻找从环境中去除药物的新方法。最重要的技术和经济解决方案之一包括对这些抗性污染物进行微生物降解。寻找能够降解布洛芬的新菌株可能是增加水中药物检测的答案之一。本研究描述了细菌菌株苏云金芽孢杆菌 B1(2015b) 去除布洛芬的能力。在以 1、3、5、7 和 9 毫克 L-1 布洛芬和 1 克 L-1 葡萄糖作为碳源的单底物和共代谢系统中培养细菌。苏云金芽孢杆菌 B1(2015b) 在单底物培养中在 232 小时内去除了高达 9 mg L-1 的布洛芬，而在共代谢培养中，药物的去除速度快了 6 倍以上。这就是为什么所检查的菌株可用于增强布洛芬的生物修复。