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Mathematical Model of Antiviral Immune Response against the COVID-19 Virus
Mathematics ( IF 2.4 ) Pub Date : 2021-06-11 , DOI: 10.3390/math9121356
Juan Carlos Chimal-Eguia

This work presents a mathematical model to investigate the current outbreak of the coronavirus disease 2019 (COVID-19) worldwide. The model presents the infection dynamics and emphasizes the role of the immune system: both the humoral response as well as the adaptive immune response. We built a mathematical model of delay differential equations describing a simplified view of the mechanism between the COVID-19 virus infection and the immune system. We conduct an analysis of the model exploring different scenarios, and our numerical results indicate that some theoretical immunotherapies are successful in eradicating the COVID-19 virus.

中文翻译:

针对 COVID-19 病毒的抗病毒免疫反应的数学模型

这项工作提出了一个数学模型来调查当前在全球范围内爆发的 2019 年冠状病毒病 (COVID-19)。该模型展示了感染动力学并强调了免疫系统的作用:体液反应和适应性免疫反应。我们建立了一个延迟微分方程的数学模型,描述了 COVID-19 病毒感染和免疫系统之间机制的简化视图。我们对探索不同场景的模型进行了分析,我们的数值结果表明,一些理论免疫疗法在根除 COVID-19 病毒方面是成功的。
更新日期:2021-06-11
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