The importance of pollution in determining human health is becoming increasingly clear, also given the dramatic consequences it has had on recent geopolitical events. Yet, the consequences of contamination are not always straightforward. In this paper, we will discuss the effects of different pollutants on different aspects of human health, in particular on the immune system and inflammation. Different environmental pollutants can have different effects on the immune system, which can then promote complex pathologies, such as autoimmune disorders and cancer. The interaction with the microbiota also further helps to determine the consequences of contamination on wellbeing. The pollution can affect vaccination efficacy, given the widespread effects of vaccination on immunity. At the same time, some vaccinations also can exert protective effects against some forms of pollution.

中文翻译：

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污染、炎症和疫苗：复杂的串扰

考虑到污染对最近的地缘政治事件产生的巨大影响，污染在决定人类健康方面的重要性正变得越来越明显。然而，污染的后果并不总是那么简单。在本文中，我们将讨论不同污染物对人类健康不同方面的影响，特别是对免疫系统和炎症的影响。不同的环境污染物会对免疫系统产生不同的影响，从而促进复杂的病理变化，例如自身免疫性疾病和癌症。与微生物群的相互作用还有助于确定污染对健康的影响。鉴于疫苗接种对免疫的广泛影响，污染会影响疫苗接种效果。同时，