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Extreme prematurity and sepsis strongly influence frequencies and functional characteristics of circulating γδ T and natural killer cells
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2021-06-10 , DOI: 10.1002/cti2.1294
Khaleda Rahman Qazi 1 , Georg B Jensen 2, 3 , Marieke van der Heiden 1 , Sophia Björkander 1 , Giovanna Marchini 4 , Maria C Jenmalm 2 , Thomas Abrahamsson 2, 3 , Eva Sverremark-Ekström 1
Affiliation  

Extremely low gestational age neonates with extremely low birthweight (ELGAN/ELBW) are highly susceptible to infection. This is linked to their relatively immature immune system which is not yet fully compatible with an extra-uterine environment. Here, we performed a longitudinal characterisation of unconventional T and natural killer (NK) cells in ELGAN/ELBW during their first months of life.

中文翻译:

极度早产和败血症强烈影响循环γδT和自然杀伤细胞的频率和功能特征

极低出生体重的极低胎龄新生儿 (ELGAN/ELBW) 极易感染。这与他们相对不成熟的免疫系统有关,该系统尚未与子宫外环境完全兼容。在这里,我们在 ELGAN/ELBW 生命的头几个月对非常规 T 细胞和自然杀伤 (NK) 细胞进行了纵向表征。
更新日期:2021-06-11
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