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Hemodialysis acutely altered interferon-gamma release assay test result and immune cell profile
Journal of Microbiology, Immunology and Infection ( IF 7.4 ) Pub Date : 2021-06-11 , DOI: 10.1016/j.jmii.2021.03.022
Denise Utami Putri, Chia-Ling Chen, Cheng-Hui Wang, Yuh-Mou Sue, Po-Chun Tseng, Chiou-Feng Lin, Ching-Wen Tsai, Yi-Jun Liu, Chih-Hsin Lee

Patients receiving hemodialysis (HD) are at risk of TB development. IGRA-positive patients showed significant decrease in quantitative IGRA result with alterations in CD3+CD4+CD45RO+, NK cell, and monocyte subsets immediately upon HD procedure. Our result suggested that the timing of IGRA testing is crucial in end-stage renal disease population.



中文翻译:

血液透析急性改变的干扰素-γ释放试验结果和免疫细胞谱

接受血液透析 (HD) 的患者有发生结核病的风险。IGRA 阳性患者的 IGRA 定量结果显着下降,CD3 + CD4 + CD45RO +、NK 细胞和单核细胞亚群在 HD 手术后立即发生改变。我们的结果表明,IGRA 检测的时机对于终末期肾病人群至关重要。

更新日期:2021-06-11
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