Aims

There is limited research focusing on how never tobacco users respond to claims associated with modified risk tobacco products (MRTPs). The purpose of the present study is twofold: (1) to identify how never tobacco users perceive hypothetical modified risk tobacco product (MRTP) claims; and (2) to assess whether these perceptions impact their intentions of using MRTPs described as “less harmful” and “less addictive.”

Method

The present study draws upon a nationally representative dataset of US adults aged ≥ 18 years (n = 850) from a cross-sectional survey (HINTS-FDA, Cycle 2, 2017). Weighted unadjusted and adjusted logistic regression analyses were performed to analyze the data.

Results

Participants who perceived tobacco products labeled as having “no additives” to be less harmful were close to three times more likely to report intentions of using “less harmful” (Adjusted OR = 2.93 [95% CI: 1.12–7.65]) and “less addictive” (Adjusted OR = 2.72 [95% CI: 1.03–7.21]) tobacco products than those who perceived them to be more/equally harmful. Participants who believed that tobacco products could be manufactured without some chemicals were over five and six times more likely to report intentions of using “less harmful” (Adjusted OR = 5.53 [95% CI: 1.59–19.25]) and “less addictive” (Adjusted OR = 6.60 [95% CI: 2.65–16.46]) tobacco products than those who were unlikely to believe it.

Conclusions

Our findings have implications for FDA’s regulation of MRTPs and provides insights regarding how the marketing of authorized MRTPs could impact population health in the future.

中文翻译：

---

美国从不吸烟的人对使用危害较小和成瘾性较低的假设性改良风险烟草产品的感知和意图

宗旨

很少有研究关注烟草使用者如何从不回应与改良风险烟草产品 (MRTP) 相关的声明。本研究的目的有两个：(1) 确定烟草使用者如何从不感知假设的改良风险烟草产品 (MRTP) 声明；(2) 评估这些看法是否会影响他们使用被描述为“危害较小”和“上瘾性较小”的 MRTP 的意图。

方法

本研究利用横断面调查（HINTS-FDA，第 2 周期，2017 年）中 18 岁以上的美国成年人（n = 850）的全国代表性数据集。进行加权未调整和调整的逻辑回归分析以分析数据。

结果

认为标记为“无添加剂”的烟草产品危害较小的参与者报告使用“危害较小”（调整后的 OR = 2.93 [95% CI：1.12–7.65]）和“更少”的意图的可能性接近三倍成瘾性”（调整后的 OR = 2.72 [95% CI：1.03–7.21]）烟草产品比那些认为它们更/同样有害的人更容易上瘾。认为可以在不使用某些化学品的情况下制造烟草产品的参与者报告使用“危害较小”（调整后的 OR = 5.53 [95% CI：1.59–19.25]）和“不易上瘾”（较少上瘾）的意图的可能性要高出五到六倍以上。调整后的 OR = 6.60 [95% CI: 2.65–16.46]) 烟草制品，而不是那些不太可能相信的人。

结论

我们的研究结果对 FDA 对 MRTP 的监管有影响，并提供了关于授权 MRTP 的营销如何影响未来人口健康的见解。