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“Intolerance of uncertainty” mediates the relationship between social profile and anxiety in both Williams syndrome and autism
Autism Research ( IF 4.7 ) Pub Date : 2021-06-10 , DOI: 10.1002/aur.2554 Mikle South 1, 2, 3 , Mary Hanley 3, 4 , Karys Normansell-Mossa 1 , Nicholas C C Russell 1 , Thomas Cawthorne 5 , Deborah M Riby 3, 4
Autism Research ( IF 4.7 ) Pub Date : 2021-06-10 , DOI: 10.1002/aur.2554 Mikle South 1, 2, 3 , Mary Hanley 3, 4 , Karys Normansell-Mossa 1 , Nicholas C C Russell 1 , Thomas Cawthorne 5 , Deborah M Riby 3, 4
Affiliation
Anxiety is the most significant mental health concern for both Williams syndrome (WS) and autism. Whilst WS and autism are characterized by some syndrome-specific social differences, less is known about cross-syndrome profiles of anxiety symptoms. Previous research has shown that Intolerance of Uncertainty (IU) is a core mechanism of anxiety maintenance for clinically anxious populations and for autistic children, adolescents, and adults. The only published study in this area for WS has shown some similar patterns—with an added emphasis on the role of sensory sensitivities—in a sample of older teens and adults (mean age = 24), with the authors highlighting the need for younger samples to consider developmental influences. Here we report a cross-syndrome, cross-sectional mediation analyses of children diagnosed with WS or autism, including data from parent surveys of 90 children with WS (n = 48) or autism (n = 42). Group differences showed higher trait levels on all measures for the autism group. Importantly, the relationship between social profile and anxiety was fully mediated by IU level for both groups. This suggests possible similar core mechanisms underlying anxiety in these conditions, and the possibility of generalized intervention approaches especially related to managing distress related to uncertainty in multiple contexts.
中文翻译:
“对不确定性的不容忍”介导了威廉姆斯综合征和自闭症的社会形象与焦虑之间的关系
焦虑是威廉姆斯综合征 (WS) 和自闭症最重要的心理健康问题。虽然 WS 和自闭症的特点是一些特定于综合征的社会差异,但对焦虑症状的跨综合征特征知之甚少。先前的研究表明,不确定性不耐受 (IU) 是临床焦虑人群和自闭症儿童、青少年和成人焦虑维持的核心机制。该领域唯一已发表的 WS 研究在年龄较大的青少年和成年人(平均年龄 = 24)样本中显示出一些类似的模式,并进一步强调感官敏感性的作用,作者强调需要更年轻的样本考虑发展影响。在这里,我们报告了对被诊断患有 WS 或自闭症的儿童的跨综合征、横断面中介分析,n = 48) 或自闭症 ( n = 42)。群体差异在自闭症组的所有测量中都显示出更高的特征水平。重要的是,社会形象和焦虑之间的关系完全由两组的 IU 水平调节。这表明在这些情况下焦虑背后可能存在类似的核心机制,以及普遍干预方法的可能性,特别是与管理与多种情况下的不确定性相关的痛苦有关。
更新日期:2021-06-10
中文翻译:
“对不确定性的不容忍”介导了威廉姆斯综合征和自闭症的社会形象与焦虑之间的关系
焦虑是威廉姆斯综合征 (WS) 和自闭症最重要的心理健康问题。虽然 WS 和自闭症的特点是一些特定于综合征的社会差异,但对焦虑症状的跨综合征特征知之甚少。先前的研究表明,不确定性不耐受 (IU) 是临床焦虑人群和自闭症儿童、青少年和成人焦虑维持的核心机制。该领域唯一已发表的 WS 研究在年龄较大的青少年和成年人(平均年龄 = 24)样本中显示出一些类似的模式,并进一步强调感官敏感性的作用,作者强调需要更年轻的样本考虑发展影响。在这里,我们报告了对被诊断患有 WS 或自闭症的儿童的跨综合征、横断面中介分析,n = 48) 或自闭症 ( n = 42)。群体差异在自闭症组的所有测量中都显示出更高的特征水平。重要的是,社会形象和焦虑之间的关系完全由两组的 IU 水平调节。这表明在这些情况下焦虑背后可能存在类似的核心机制,以及普遍干预方法的可能性,特别是与管理与多种情况下的不确定性相关的痛苦有关。